Glioblastoma multiforme (GBM) is a grade-IV brain tumor and the most common, aggressive and malignant of all gliomas.

It often develops in the frontal and temporal lobes of the brain’s cerebral hemispheres and frequently strikes men between 50 and 70 years of age.

Treatment for GBM is difficult due to many factors, including tumor localization deep within the brain, the migration of malignant cells to surrounding healthy brain tissue, and the limited response to conventional therapies. As a result, the prognosis is poor, with the majority of patients succumbing within 15 months following diagnosis.

Symptoms

• Headache
• Seizures
• Vomiting
• Memory loss
• Speech problems
• Visual problems
• Physical weakness
• Loss of muscle control
• Changes in personality
• Cognitive decline